ODCs

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1 associated gene
No signs/symptoms info

PROTEIN INTERACTIONS: 1

2 OMIM references -
1 associated gene
11 signs/symptoms

Moderately severe hemophilia A

Hereditary thrombophilia due to congenital protein C deficiency


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	F8	(0.66)	PROC

Citations in the biomedical literature:

Moderately severe hemophilia A		Hereditary thrombophilia due to congenital protein C deficiency
	Synonym(s): - Moderately severe factor VIII deficiency		Synonym(s): - Hereditary thrombophilia due to PC deficiency

	Classification (Orphanet): - Rare genetic disease - Rare hematologic disease		Classification (Orphanet): - Rare bone disease - Rare genetic disease - Rare hematologic disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: x-linked recessive		Epidemiological data: Class of prevalence: 1-9 / 1 000 000 Average age onset: childhood Average age of death: - Type of inheritance: autosomal recessive

	External references: No OMIM references No MeSH references		External references: 2 OMIM references - No MeSH references

Hereditary thrombophilia due to congenital protein C deficiency
	Very frequent - Autosomal recessive inheritance Frequent - Purpura / petichiae - Skin hypoplasia / aplasia / atrophy - Thin skin - Venous thrombosis / phlebitis / thrombophlebitis Occasional - Abnormal pigmentary skin changes / skin pigmentation anomalies - Cerebral vascular anomalies - Chronic skin infection / ulcerations / ulcers / cancrum - Gangrena / necrosis - Pulmonary thromboembolism - Varices / varicous veins / venous insufficiency
Moderately severe hemophilia A
(no data available)